Butler's Wharf is an English historic building on the south bank of the River Thames, just east of London's Tower Bridge, now housing luxury flats and restaurants. Lying between the picturesque street Shad Thames and the Thames Path, it overlooks both the bridge and St Katharine Docks on the other side of the river. Butler's Wharf is also used as a term for the surrounding area.

Butler's Wharf was built between 1871-73 as a shipping wharf and warehouse complex, accommodating goods unloaded from ships using the port of London. It contained what was reputedly the largest tea warehouse in the world. During the 20th century, Butler's Wharf and other warehouses in the area fell into disuse.

From 1975-78, the artists' space at 2B Butler's Wharf was a key venue for early UK video art and performance art.

In 1984, Butler's Wharf and the portion of Shad Thames running behind it featured prominently in the Doctor Who serial Resurrection of the Daleks.

Since the 1980s, Butler's Wharf has been transformed from a derelict site into luxury flats, with restaurants and shops on the ground floor.